What is the new breast cancer drug anastrozole? How it works

With 80% of those diagnosed with breast cancer are post-menopausal, it is hoped that this preventative drug will make a drastic impact by preventing the disease. The drug, which is off-patent, has been shown in trials to reduce the incidence of the disease in post-menopausal women at increased risk of the disease by almost 50%. Arimidex lowers the amount of the hormone called estrogen that is in your body.

  • Most people can eat and drink normally when taking anastrozole.
  • By incorporating Anastrozole into your steroid cycle, you can effectively manage estrogen levels, minimizing potential side effects and maximizing the benefits of your hard work in the gym.
  • Anastrozole is an aromatase inhibitor with the chemical formula C17H19N5.
  • Officials have estimated that if 25% of eligible women in England take up the offer – and half of those take the drug for the recommended five years – then 2,000 cases would be prevented over their lifetimes.

This is because the brand name might be different in the country you are visiting. Restrictions might also apply to medicines that need tobe injected. The move was facilitated via a pioneering programme led by NHS England and involving a number of national bodies including NICE, the MHRA and the National Institute for Health and Care Research.

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The amount of time cancer did not worsen or spread in post-menopausal women with secondary HR+ breast cancer on letrozole vs. tamoxifen. Additionally, the data suggested that letrozole improved survival for most patients by 14 months compared with tamoxifen4. This means that it attaches to the aromatase enzyme temporarily, and then disengages. This can lead to a ‘rebound’ of oestrogen levels if it is not dosed correctly or the protocol is not optimal. Having raised oestrogen causes a negative feedback loop which results in suppression of testosterone production.

  • The Arimidex safety profile in these 3 studies was consistent with the known safety profile established in postmenopausal women with hormone receptor-positive early breast cancer.
  • By monitoring your health closely and adjusting Anastrozole dosage as needed, you can minimize the chances of experiencing unwanted side effects and maximize the benefits of using this powerful aromatase inhibitor.
  • If you have, or suspect you may have, a health problem you should consult your doctor.
  • The majority of the side effects I had with letrozole restarted after I began taking exemestane, although each of these were at a lower level than previously.
  • Breast cancer remains to be the most prevalent cancer in England.

There were no clinically significant interactions with bisphosphonates (see section 5.1). Arimidex has not been investigated in breast cancer patients with moderate or severe hepatic impairment. Treatment should be based on a benefit-risk evaluation for the individual patient.

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Arimidex is a hormone therapy drug used to treat breast cancer in post-menopausal women. It works by decreasing the amount of estrogen in the body and slowing or reversing the growth of certain types of breast cancer cells. Anastrozole’s ability to reduce estrogen levels plays a crucial role in restoring natural testosterone production during PCT. With lower estrogen levels, the body can more effectively utilize the testosterone produced, promoting muscle growth and strength gains even after the steroid cycle has ended. Controlling estrogen levels during steroid cycles is of utmost importance to prevent side effects such as gynecomastia, water retention, and an increased risk of cardiovascular disease. Elevated estrogen levels can also negatively impact muscle growth and strength, hindering your progress despite the use of anabolic steroids.

Now it’s time to take control of your estrogen levels and unlock your full potential with the power of Anastrozole. Yes, Arimidex is the brand name of anastrozole, a medication used to treat breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by blocking the production of estrogen in the body. A total of 764 patients were randomised to receive either a single daily dose of 1 mg or 10 mg of Arimidex or megestrol acetate 40 mg four times a day. Time to progression and objective response rates were the primary efficacy variables.

“Thanks to this initiative, we hope that greater access to anastrozole could enable more women to take risk-reducing steps if they’d like to, helping them live without fear of breast cancer,” she added. The most common side effects of the medication are hot flushes, feeling weak, pain or stiffness in the joints, arthritis, skin rash, nausea, headache, osteoporosis and depression. Specialist nurses and charities have welcomed an announcement that the breast cancer drug anastrozole has been ‘repurposed’ for use to prevent the disease in England.

Arimidex / Anastrozole to buy on our site:

The athlete should monitor the level of their hormones throughout the course. “We’ve already seen the positive effect anastrozole can have in treating the disease when it has been detected in post-menopausal women and now we can use it to stop it developing at all in some women. The moveadds to the NHS’s armoury of preventative breast cancer medication with tamoxifen and raloxifene already licenced to prevent breast cancer. Around 47,000 women in England are diagnosed with breast cancer each year and it’s the most common cancer in the UK. GPs have hit out at NHS England for failing to warn the profession ahead of a breast cancer drug announcement last week that a senior official advised patients to ‚discuss with your GP‘.

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The rate of prolonged (more than 24 weeks) stable disease, the rate of progression, and survival were also calculated. In both studies there were no significant differences between treatment arms with respect to any of the efficacy parameters. AIs offer an effective treatment option for secondary HR+ breast cancer in post-menopausal Spectros 14 IU Spectrum Pharma women, or in some cases pre-menopausal women and men. Side effects may occur, but open communication with the care team can help patients to manage these challenges and improve outcomes. Aromatase inhibitors are a class of drugs that can be used to treat hormone receptor-positive (HR+) subtypes of breast cancer1.

What should I take Arimidex with?

Our product range includes a wide range of ‘Prescription Only Medicines’ and Consumer Healthcare ‘P’ (Pharmacy only) and ‘GSL’ (General Sales listing) products. GSL products are suitable for general sale in all retail outlets. Our Consumer Healthcare range has been recently been updated to provide strong branding and ‘on the shelf’ retail presence to encourage customer brand loyalty and increase consumer sales. However, this drug has also found wide application in sports practice, in particular during courses designed for muscle growth, in order to prevent the phenomenon of kickback. Anastrozole also minimizes the effect of androgen receptors, which allows you to minimize or completely eliminate the symptoms of gynecomastia. During the surgery, lymph nodes were removed and after testing were negative of any cancer cells, so I continued to be treated as a stage 1 breast cancer patient.